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Table 6: Mean QT and QTc changes in msec (90% CI) from baseline relative to placebo at 1 hour post-dose with different methodologies to correct for the effect of heart rate. Drug/Dose QT Uncorrected

Approved by the FDA in 1998, sildenafil (Viagra) revolutionized the way we think about — and treat — erectile dysfunction (ED), largely because it is effective and easy to use. In 2003, the FDA approved two closely related drugs, vardenafil (Levitra) and tadalafil (Cialis). Five years later, in January 2008, low-dose Cialis for daily use came onto the market, creating an option that — theoretically, at least — makes having sex a possibility without advance planning.All three drugs work in a similar fashion, by affecting the normal physiology of the penis. In particular, they block PDE5, an enzyme that breaks down the erection-producing chemical cyclic guanosine monophosphate. This enables the penis to fill with blood and to stay erect long enough for intercourse. Of course, it’s important to realize that none of these drugs is an aphrodisiac. You must feel sexually aroused in order for them to work.The main differences between the three drugs have to do with timing: how quickly they begin to work, and how long their effects last (see Table 4). The biggest divide lies between Cialis for daily use, which keeps a steady supply of the drug in the bloodstream, and the as-needed dosing offered by the original form of Cialis, as well as by Levitra and Viagra. Among the nondaily pills, Levitra may start working slightly faster than Viagra (within a half-hour instead of an hour) although the FDA says that like Viagra, it should be taken about an hour before sexual activity. Some studies suggest that Levitra may help some men who don’t respond to Viagra. And while some doctors are skeptical about this claim, there’s no harm in trying Levitra or Cialis if Viagra doesn’t work for you. mesylate), Minipress (prazosin HCl), Uroxatral (alfuzosin HCl), on line viagra For payment we accept only credit/debit cards such as VISA, MasterCard, Amex, JCB and Dinners.Hepatic Impairment20 mg Cialis tablet

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Ophthalmologic — blurred vision, changes in color vision, conjunctivitis (including conjunctival hyperemia), eye pain, lacrimation increase, swelling of eyelids

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient. levitra original Keep this medication in the container it came in, tightly closed, and out of reach of children. Store the tablets at room temperature and away from excess heat and moisture (not in the bathroom). Store the suspension at room temperature or in a refrigerator, but do not freeze it. Throw away any unused suspension after 60 days. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.Stop any sexual activity if you experience any chest pain, dizziness, or nausea during sex and get medical help immediately. Sex may put strain on your heart, especially if it is already weak from heart disease.Concomitant Use of Potent Inhibitors of Cytochrome P450 3A4 (CYP3A4)

Immediately telephone your doctor or Poisons Information Centre (telephone in Australia 13 11 26; in New Zealand 0800 POISON or 0800 764 766) for advice if you think that you or anyone else may have taken too much Viagra. Do this even if there are no signs of discomfort. Benign prostatic hyperplasia

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