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Erection of the penis is initiated by the relaxation of smooth muscle in the corpus cavernosum, one of a pair of sponge-like regions in the penis. When aroused, nitric oxide is released from nerve endings and endothelial cells in the corpus cavernosum. Nitric oxide activates the enzyme guanylate cyclase resulting in increased synthesis of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the corpus cavernosum. The cGMP triggers smooth muscle relaxation, increasing blood flow into the penis, resulting in erection. buy viagra no prescription Stop using sildenafil and call your doctor at once if you have a serious side effect such as:

liver disease, kidney disease (or if you are on dialysis);

cialis 20 mg duration vomitingIt's not known if sildenafil is excreted in breast milk. Ask your doctor if it's safe to breastfeed while taking Viagra.Generic Cialis starts working within 45 minutes of taking and lasts up to 36 hours.

Ingredient Name Basis of Strength Strength

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