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Levitra significantly improved the overall per-patient rate of achieving an erection sufficient for penetration (SEP2) (47% on 10 mg and 48% on 20 mg Levitra compared to 22% on placebo; p <0.0001). natural viagra For Sexual Dysfunction, SSRI Induced "I am 29 and Ihave problem of coming early in sex. I tried 50 mg and the effect was awesome."Urticaria, Stevens-Johnson syndrome2, Exfoliative dermatitis2Viamedic - In Business 14 YRS!!!
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Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and corpus cavernosal smooth muscle. This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells. Cyclic GMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum. The inhibition of phosphodiesterase type 5 (PDE5) enhances erectile function by increasing the amount of cGMP. Tadalafil inhibits PDE5. Because sexual stimulation is required to initiate the local release of nitric oxide, the inhibition of PDE5 by tadalafil has no effect in the absence of sexual stimulation.Drug Interaction Classification
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