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REFERENCES: WARNING: Cyclosporine is a drug that reduces the body's ability to fight illness/disease (an immunosuppressant), leaving patients vulnerable to infection or other problems (including cancers such as lymphoma). Using other drugs that treat organ transplant rejection along with this drug may increase these tendencies. Cyclosporine can also cause high blood pressure and kidney problems. The risk of both problems increases with higher doses and longer treatment with this drug. Psoriasis patients who have had certain previous treatments (e.g., coal tar, methotrexate, PUVA, UVB, or other radiation therapy) are at increased risk to develop skin cancer. Therefore, cyclosporine must be given only under close medical supervision. Because different brands deliver different amounts of medication, do not switch brands of cyclosporine without your doctor's permission and directions. Laboratory tests (e.g., kidney function tests, blood tests) may be performed to monitor your progress.
dizziness, feeling light-headed, fainting, fast or pounding heartbeat;Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.Tell your doctor if you are taking any medicines, including those bought over-the-counter and herbal medicines, before you start treatment with Diclofenac Sodium EC. Similarly, check with your doctor or pharmacist before you take any new medicines while you are taking Diclofenac Sodium EC. Diclofenac Sodium EC may increase the blood levels of the following medicines: - lithium - digoxin - methotrexate. People taking Diclofenac Sodium EC with any of the above should be closely monitored by their doctor. There may be an increased risk of bleeding if Diclofenac Sodium EC is taken with blood-thinning or anti-clotting medicines (anticoagulants) such as warfarin. People taking Diclofenac Sodium EC with an anticoagulant should be closely monitored by their doctor. There may be an increased risk of side effects such as stomach irritation if Diclofenac Sodium EC is taken with corticosteroids such as prednisolone. Diclofenac Sodium EC should not be taken with any other NSAID, eg ibuprofen, as this increases the risk of side effects, particularly on the gut. Ciclosporin may increase the blood level of Diclofenac Sodium EC, and your doctor may prescribe a lower than normal dose of diclofenac if you are taking ciclosporin. There may be an increased risk of side effects on the kidneys if Diclofenac Sodium EC is taken with any of the following medicines: - ciclosporin - ACE inhibitors, eg enalapril - diuretics, eg frusemide (furosemide). Diclofenac Sodium EC may reduce the blood pressure lowering effects of diuretics such as frusemide (furosemide). There may potentially be an increased risk of seizures if Diclofenac Sodium EC is taken together with quinolone antibiotics such as ciprofloxacin.
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Most Important Fact about Diclofenac Sodium EC You should have frequent checkups with your doctor if you take Diclofenac Sodium EC regularly. Ulcers or internal bleeding can occur without warning. Diclofenac Sodium EC precautions if you are pregnant or breastfeeding Do not take Diclofenac Sodium EC late in your pregnancy; it could harm the baby. Check with your doctor before taking Diclofenac Sodium EC early in pregnancy; it should be used only if necessary. Diclofenac Sodium EC does appear in breast milk and could affect a nursing infant. If Diclofenac Sodium EC is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with it is finished. Special warnings about Diclofenac Sodium EC Diclofenac Sodium EC may cause dizziness and so may affect your ability to drive or operate machinery safely. Do not drive or operate machinery until you know how Diclofenac Sodium EC affects you and you are sure it won\'t affect your performance. People with impaired kidney, liver or heart function who are taking Diclofenac Sodium EC should have their kidney function monitored. During long-term treatment, routine blood tests are recommended to monitor kidney function, liver function and levels of blood components, particularly in the elderly. Diclofenac Sodium EC may mask the signs and symptoms of infection. This may make you think mistakenly that an infection is getting better when it isn\'t, or that an infection is less serious than it is. For this reason you should tell your doctor if you get an infection while you are taking Diclofenac Sodium EC. It is important that people with a history of disorders affecting the stomach or intestines are closely monitored by a doctor while taking Diclofenac Sodium EC, particularly if elderly. Consult your doctor immediately if you experience side effects such as stomach pain, indigestion, heartburn or signs of bleeding in the stomach or intestines, eg blood in the stools, while taking Diclofenac Sodium EC. Close medical supervision is important in people suffering from severe impairment of liver function. Common (1% to 10%): Impaired concentration, headache, somnolence, disturbance in attention, paresthesia (included numbness/tingling)
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